AMES, Iowa (AP) — Brock Purdy passed for 302 yards and two touchdowns, Breece Hall ran for 135 yards and two scores and No. 24 Iowa State beat Texas Tech 31-15. The Cyclones opened conference play with three straight wins for the first time since 2002 and only the second time since 1950. Purdy finished 32 of 43 with no interceptions. He also ran seven times for 42 yards. The Cyclones rolled up 516 yards of total offense and held Texas Tech under 100 yards until early in the fourth quarter.
UNDATED (AP) — The Red River rivalry lived up to its hype on Saturday despite the rankings of the two teams. Spencer Rattler threw a 25-yard touchdown pass to Drake Stoops in the fourth overtime before unranked Oklahoma picked off a pass in the end zone to secure a wild 53-45 win against No. 22 Texas. Rattler’s successful completion on the required 2-point conversion didn’t matter when Sam Ehlinger’s pass was intercepted in the end zone by Tre Brown to end just the second Big 12 game to go four OTs.
In other top 25 action:
— What was supposed to be Clemson’s stiffest test of the regular season turned into a rout as Trevor Lawrence threw for three touchdowns in the top-ranked Tigers’ 42-17 dismantling of No. 7 Miami. Travis Etienne rushed for 149 yards and two scores, including a 72-yard burst down the left sidelines as the Tigers opened 4-0 for a sixth straight season. The Hurricanes mustered just 210 yards after averaging 499 in their first three games.
— Najee Harris ran for 206 yards and five touchdowns for second-ranked Alabama in a 63-48 win over Mississippi, the highest-scoring regulation game in SEC history. Ole Miss stayed close until Receiver DeVonta Smith went 14 yards for a touchdown run to make it 56-45 with 3:16 left. Harris closed the scoring with a 39-yard TD run.
— Stetson Bennett threw two touchdown passes and ran for another score as third-ranked Georgia whipped No. 14 Tennessee, 44-21. Bennett sealed the victory with a 1-yard TD flip to 305-pound nose tackle Jalen Carter, who was supposedly in the game as an extra blocker. The Bulldogs scored 27 unanswered points in the second half to beat a ranked SEC team for the second straight win.
— No. 21 Texas A&M knocked off fourth-ranked Florida, 41-38 on Seth Small’s 26-yard field goal as time expired. Isaiah Spiller rushed for 174 yards and two touchdowns for the Aggies, who tied it up when Kellen Mond threw a 51-yard pass to Caleb Chapman for a tying TD with about 4½ minutes to go.
— No. 5 Notre Dame posted a 42-26 rout of Florida State as Kyren Williams ran for 185 yards and two touchdowns. Williams shook off a fumble on his first carry to pick up 130 yards and both his TDs by halftime. Ian Book completed 16 of 25 passes for 201 yards and two touchdowns and ran for 58 yards and another score for the Irish.
— Michael Carter ran for a career-high 214 yards and two touchdowns to help eighth-ranked North Carolina beat No. 19 Virginia Tech 56-45. Javonte Williams also ran for a career-best 169 yards and two scores of his own. UNC finished with its highest scoring output ever against the Hokies along with 656 total yards for the No. 2 total ever posted against Virginia Tech’s defense.
— Anders Carlson atoned for a missed 34-yard field goal by drilling a 39-yarder with seven seconds left to lift No. 13 Auburn over Arkansas, 30-28. Freshman Tank Bigsby ran for 146 yards to help the Tigers rebound from last weekend’s loss to Georgia. Feleipe Franks, who passed for 318 yards and four touchdowns for the Razorbacks.
— Zach Wilson threw for 292 yards and two touchdowns for 15th-rated BYU in a 27-20 win against UTSA. Tyler Allgeier rushed 116 yards and another score to help the Cougars improve to 4-0 for the first time in six years.
— The defending champs absorbed their second loss of the season as Connor Bazelak (BAY’-zeh-lak) threw for 406 yards and four touchdowns in Missouri’s 45-41 win over 17th-ranked LSU. Missouri’s maligned defense stopped No. 17 LSU four times at the 1-yard line in the final minute. Larry Rountree added 119 yards rushing and Tyler Badie had touchdowns on the ground and through the air for Mizzou.
NASHVILLE, Tenn. (AP) — The Tennessee Titans and the New England Patriots had no positive COVID-19 tests Saturday, and both teams are getting back into their facilities. The Titans will be returning for the first time since the NFL closed them down Sept. 29. The Patriots had worked remotely the past three days. The Titans now have had no positive test results four of the past six days. The Titans are scheduled to play Buffalo on Tuesday night, with the Patriots hosting Denver on Monday.
Houston and Tampa Bay are set to open their AL Championship Series in San Diego, with Astros left-hander Framber Valdez opposing 2018 AL Cy Young Award winner Blake Snell. The Rays are seeking revenge after Houston beat them in five games in the AL Division Series last year. The Astros are in the ALCS for the fourth straight year, looking for a third trip to the World Series in that span. After going 29-31 during the regular season, Houston is 5-1 in the playoffs after eliminating AL West champion Oakland in four games in the ALDS at Dodger Stadium.