— Jimmy Garoppolo threw two long touchdown passes and the 49ers began a difficult three-game stretch of division-leading opponents by blasting the Packers, 37-8. Garoppolo connected on a 42-yard touchdown strike to Deebo Samuel in the second quarter and a 61-yarder to George Kittle in the third to help San Francisco improve to 10-1. Aaron Rodgers lost a fumble on the opening drive, was sacked five times and was held to 104 yards passing as Green Bay fell to 8-3.
— Allen Robinson scored a TD and had a season-high 131 yards receiving as the Bears won for the second time in three games, 19-14 over the Giants. Khalil Mack had a strip-sack deep in New York territory to set up Mitchell Trubisky’s two-yard touchdown run that put Chicago ahead 19-7. Trubisky threw for a season-high 278 yards, one touchdown and two interceptions as the 5-6 Bears dealt the 2-9 Giants their seventh consecutive loss.
- The Saints coughed up a 31-18 lead before Will Lutz drilled a 33-yard field goal as time expired to give New Orleans a 34-31 victory over the Panthers.
- The Patriots became the first team to hold Dallas without a touchdown this season as New England picked up a 13-9 win over the Cowboys to improve to 10-1.
- Rashaad Penny ran for a career-best 129 yards, including a 58-yard touchdown that helped the Seahawks knock off the Eagles, 17-9.
- The Bills improved to 8-3 as Josh Allen threw for two touchdowns and Shaq Lawson had two of Buffalo’s four sacks in a 20-3 win over the Broncos.
- The Titans scored four touchdowns over six offensive plays in the third quarter to turn a close game into an eventual 42-20 romp over the Jaguars.
- The Raiders’ three-game winning streak is over after Sam Darnold passed for two touchdowns and ran for another in the Jets’ 34-3 rout of Oakland.
- Devlin “Duck” Hodges took over for struggling Mason Rudolph and threw a 79-yard touchdown pass to James Washington that carried the Steelers to a 16-10 victory over the winless Bengals.
- Jarvis Landry had 10 receptions for 148 yards and two touchdowns against his former team in leading the Browns to their third straight win, 41-24 over the Dolphins.
- Quinton Dunbar intercepted Jeff Driskel in the final minute before Dustin Hopkins hit a tiebreaking, 39-yard field goal with 16 seconds left to push the Redskins past the Lions, 19-16.
- Defensive lineman Vita Vea turned receiver to haul in his first career touchdown in the Buccaneers’ 35-22 victory against the Falcons.